Gastric pH >4 lasted for 3 min after water and for 12 min after antacids; it remained >4 until the end of recording in: 4/12 subjects with ranitidine, 11/12 with rabeprazole, and all with omeprazole and esomeprazole.While the duration of action was shortest for water, the authors noted at the outset of their study that the onset of action is of key importance when it comes to treatment:
Onset of action of antisecretory agents is of pivotal importance for patients with gastroesophageal reflux disease (GERD) treated "on demand."What would you rather do? Get instant relief with a glass of water, which has loads of side benefits to your health, or wait between 50 minutes to 175 minutes (close to 3 hours!) as the excess acid burns the lining of your stomach, using a chemical class of drugs which have the potential to cause the following unintended, adverse side effects:
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